Differential effects of heat in the phases of the light-dark cycle in the activity-based anorexia model.

作者: Ignacio Roura , Ángela Fraga , Emilio Gutiérrez

DOI: 10.1002/EAT.23363

关键词: ChemistryAnorexiaCircadian rhythmAnorexia nervosa (differential diagnoses)Body weightDifferential effectsDark cycleAnimal scienceWeight lossWeight gain

摘要: Background: This research builds on the studies ambient temperature as a key influence in recovery of rodents exposed to activity-based anorexia (ABA) model. The ABA model is an experimental paradigm which under restricted feeding schedule and with free access activity wheel show signs that parallel those nervosa humans. Objective: present study focuses effects applying heat during different phases dark–light cycle levels, body weight, food intake, temperature, rates 30 male rats submitted ABA. Method: After reaching 20% weight loss criterion, animals were randomly assigned three conditions: (a) continuous warming, (b) warming exclusively light phase, or (c) dark phase. Results: Differential found depending modalities warming: comparison either significatively decreased activity, facilitated gain, maintained temperature. Transient both groups warmed periods exclusively. Discussion: results suggest did not promote Evidence about beneficial are line previous reinforces adding external useful tool treatment nervosa.

参考文章(42)
Caroline Davis, Eating Disorders and Hyperactivity: A Psychobiological Perspective: The Canadian Journal of Psychiatry. ,vol. 42, pp. 168- 175 ,(1997) , 10.1177/070674379704200207
Linda A. W. Verhagen, Mieneke C. M. Luijendijk, Jan-Willem de Groot, Linda P. G. van Dommelen, Anne G. Klimstra, Roger A. H. Adan, Tom A. P. Roeling, Anticipation of meals during restricted feeding increases activity in the hypothalamus in rats. European Journal of Neuroscience. ,vol. 34, pp. 1485- 1491 ,(2011) , 10.1111/J.1460-9568.2011.07880.X
Gladys Stella Martínez, Regulación circadiana del comportamiento: diferencias entre especies diurnas y nocturnas Universitas Psychologica. ,vol. 8, pp. 487- 496 ,(2009)
Olaia Carrera, María Cerrato, Emilio Gutiérrez, Ángela Fraga, Belén De Pedro, Effect of auditory isolation on activity-based anorexia Psicothema. ,vol. 24, pp. 416- 421 ,(2012)
Olaia Carrera, Ángela Fraga, Ricardo Pellón, Emilio Gutiérrez, Rodent model of activity-based anorexia Current protocols in protein science. ,vol. 67, ,(2014) , 10.1002/0471142301.NS0947S67
Stephan Zipfel, Katrin E Giel, Cynthia M Bulik, Phillipa Hay, Ulrike Schmidt, Anorexia nervosa: aetiology, assessment, and treatment The Lancet Psychiatry. ,vol. 2, pp. 1099- 1111 ,(2015) , 10.1016/S2215-0366(15)00356-9
J HILLEBRAND, C DERIJKE, J BRAKKEE, M KAS, R ADAN, Voluntary access to a warm plate reduces hyperactivity in activity-based anorexia Physiology & Behavior. ,vol. 85, pp. 151- 157 ,(2005) , 10.1016/J.PHYSBEH.2005.03.017
V. Delvenne, M. Kerkhofs, J. Appelboom-Fondu, F. Lucas, J. Mendlewicz, Sleep polygraphic variables in anorexia nervosa and depression: a comparative study in adolescents. Journal of Affective Disorders. ,vol. 25, pp. 167- 172 ,(1992) , 10.1016/0165-0327(92)90002-N
Ralph E. Mistlberger, Food-anticipatory circadian rhythms: concepts and methods. European Journal of Neuroscience. ,vol. 30, pp. 1718- 1729 ,(2009) , 10.1111/J.1460-9568.2009.06965.X
Regina C. Casper, The 'drive for activity' and "restlessness" in anorexia nervosa: potential pathways. Journal of Affective Disorders. ,vol. 92, pp. 99- 107 ,(2006) , 10.1016/J.JAD.2005.12.039