Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children*
作者： John W. Berkenbosch , Patricia C. Wankum , Joseph D. Tobias
DOI: 10.1097/01.PCC.0000163680.50087.93
关键词: Clinical trial 、 Anesthesia 、 Radionuclide imaging 、 Dexmedetomidine 、 Prospective cohort study 、 Chloral hydrate 、 Sedation 、 Prospective evaluation 、 Medicine 、 Pediatrics, Perinatology, and Child Health 、 Critical Care and Intensive Care Medicine
摘要: Objective:Children often require sedation for lengthy noninvasive procedures. Conventional agents such as chloral hydrate, benzodiazepines, or barbiturates have been associated with failure, respiratory depression, and paradoxic agitation. Dexmedetomidine is a newer α2-adrenergic receptor
lww.com 
sci-hub.se 参考文章(21)
Section on Anesthesiology, Guidelines for the Elective Use of Conscious Sedation, Deep Sedation, and General Anesthesia in Pediatric Patients Pediatrics. ,vol. 76, pp. 317- 321 ,(1985)
Joseph D. Tobias, John W. Berkenbosch, Sedation during mechanical ventilation in infants and children: dexmedetomidine versus midazolam. Southern Medical Journal. ,vol. 97, pp. 451- 455 ,(2004) , 10.1097/00007611-200405000-00007
Joseph D. Tobias, John W. Berkenbosch, Pierantonio Russo, Additional experience with dexmedetomidine in pediatric patients. Southern Medical Journal. ,vol. 96, pp. 871- 875 ,(2003) , 10.1097/01.SMJ.0000053557.75799.09
R. Venn, P. Newman, R. Grounds, A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit. Intensive Care Medicine. ,vol. 29, pp. 201- 207 ,(2003) , 10.1007/S00134-002-1579-9
JD Strain, JB Campbell, LA Harvey, LC Foley, IV Nembutal: safe sedation for children undergoing CT American Journal of Roentgenology. ,vol. 9, pp. 955- 959 ,(1988) , 10.2214/AJR.151.5.975
Harry Scheinin, Marja-Leena Jaakola, Sari Sjövall, Timo Ali-Melkkilä, Seppo Kaukinen, Jari Turunen, Jussi Kanto, Intramuscular dexmedetomidine as premedication for general anesthesia. A comparative multicenter study. Anesthesiology. ,vol. 78, pp. 1065- 1075 ,(1993) , 10.1097/00000542-199306000-00008
Anne M. Hubbard, Richard I. Markowitz, Barbara Kimmel, Margaret Kroger, Mary Beth Bartko, Sedation for pediatric patients undergoing CT and MRI. Journal of Computer Assisted Tomography. ,vol. 16, pp. 3- 6 ,(1992) , 10.1097/00004728-199201000-00002
R. M. Venn, C. J. Bradshaw, R. Spencer, D. Brealey, E. Caudwell, C. Naughton, A. Vedio, M. Singer, R. Feneck, D. Treacher, S. M. Willatts, R. M. Grounds, Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit. Anaesthesia. ,vol. 54, pp. 1136- 1142 ,(1999) , 10.1046/J.1365-2044.1999.01114.X
Tariq A. Khasawinah, Alejandro Ramirez, John W. Berkenbosch, Joseph D. Tobias, Preliminary experience with dexmedetomidine in the treatment of cyclic vomiting syndrome American Journal of Therapeutics. ,vol. 10, pp. 303- 307 ,(2003) , 10.1097/00045391-200307000-00012
L. Martí-Bonmatí, C. L. Ronchera-Oms, C. Casillas, C. Povatos, C. Torrijo, N. V. Jiménez, Randomised double-blind clinical trial of intermediate- versus high-dose chloral hydrate for neuroimaging of children Neuroradiology. ,vol. 37, pp. 687- 691 ,(1995) , 10.1007/BF00593395