Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
作者： José Luis de la Pompa , Luika A. Timmerman , Hiroaki Takimoto , Hiroki Yoshida , Andrew J. Elia
DOI: 10.1038/32419
关键词: Endocardial cushion formation 、 Endocrinology 、 Transcription factor 、 Cardiac Jelly 、 Internal medicine 、 Endocardium 、 Cell biology 、 Heart valve 、 Morphogenesis 、 Biology 、 Calcineurin 、 Endothelium
摘要: … -ATc gene fail to develop normal cardiac valves and septa and die of circulatory failure before day 14.5 of development. NF-ATc is … events appear to activate NF-ATc: it is localized to the …
nature.com
harvard.edu
sci-hub.se 参考文章(25)
Albelda Sm, Kennedy G, Buck Ca, DeLisser H, Chen A, Edelman Jm, Shen Hm, Baldwin Hs, Mickanin C, Cell adhesion receptors and early mammalian heart development: an overview. Comptes Rendus De L Academie Des Sciences Serie Iii-sciences De La Vie-life Sciences. ,vol. 316, pp. 838- ,(1993)
R B Runyan, J D Potts, R V Sharma, C P Loeber, J J Chiang, R C Bhalla, Signal transduction of a tissue interaction during embryonic heart development. Molecular Biology of the Cell. ,vol. 1, pp. 301- 313 ,(1990) , 10.1091/MBC.1.3.301
Neil A. Clipstone, Gerald R. Crabtree, Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation Nature. ,vol. 357, pp. 695- 697 ,(1992) , 10.1038/357695A0
Jun Liu, Jesse D. Farmer, Willam S. Lane, Jeff Friedman, Irving Weissman, Stuart L. Schreiber, Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes Cell. ,vol. 66, pp. 807- 815 ,(1991) , 10.1016/0092-8674(91)90124-H
Marco W. Schilham, Mariëtte A. Oosterwegel, Petra Moerer, Jing Ya, Piet A. J. de Boer, Marc van de Wetering, Sjef Verbeek, Wouter H. Lamers, Ada M. Kruisbeek, Ana Cumano, Hans Clevers, Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4 Nature. ,vol. 380, pp. 711- 714 ,(1996) , 10.1038/380711A0
Steffan N. Ho, Daryl J. Thomas, Luika A. Timmerman, Xu Li, Uta Francke, Gerald R. Crabtree, NFATC3, A LYMPHOID-SPECIFIC NFATC FAMILY MEMBER THAT IS CALCIUM-REGULATED AND EXHIBITS DISTINCT DNA BINDING SPECIFICITY Journal of Biological Chemistry. ,vol. 270, pp. 19898- 19907 ,(1995) , 10.1074/JBC.270.34.19898
Chi-chung Hui, Alexandra L. Joyner, A Mouse Model of Greig Cephalopolysyndactyly Syndrome: The extra-toesJ Mutation Contains an Intragenic Deletion of the Gli3 Gene Nature Genetics. ,vol. 3, pp. 241- 246 ,(1993) , 10.1038/NG0393-241
M. Kirby, T. Gale, D. Stewart, Neural crest cells contribute to normal aorticopulmonary septation Science. ,vol. 220, pp. 1059- 1061 ,(1983) , 10.1126/SCIENCE.6844926
John Gubbay, Jérôme Collignon, Peter Koopman, Blanche Capel, Androulla Economou, Andrea Münsterberg, Nigel Vivian, Peter Goodfellow, Robin Lovell-Badge, A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes Nature. ,vol. 346, pp. 245- 250 ,(1990) , 10.1038/346245A0
J. I. E. Hoffman, Incidence of congenital heart disease: I. Postnatal incidence Pediatric Cardiology. ,vol. 16, pp. 103- 113 ,(1995) , 10.1007/BF00801907