Analyzing Phanerochaete chrysosporium gene expression patterns controlling the molecular fate of lignocellulose degrading enzymes

作者: Ayyappa Kumar Sista Kameshwar , Wensheng Qin

DOI: 10.1016/J.PROCBIO.2017.10.007

关键词: BiologyGene expressionGenomeRNA splicingChromatinHistoneTranscription factorGenePhanerochaeteBiochemistryGenetics

摘要: Abstract The outstanding degrading abilities of Phanerochaete chrysosporium is solely dependent on its lignocellulolytic, aromatic compound and detoxifying enzymes. However, the gene expression protein turnover lignocellulolytic enzymes are controlled at cellular level by various genes involved in information storage processing KOG group. Understanding patterns mechanisms regulation lignocellulose will significantly help strain improvement developing recombinant strains. To study common patterns, we have retrieved P. datasets from NCBI GEO analyzed using GeneSpring® software based genome wide annotations JGI-MycoCosm database. Statistically significant obtained our analysis were separated into replication, repair recombination, chromatin structure dynamics, transcription factors, RNA modification translation, ribosomal biogenesis processes. We observed encoding for DNA damage, mRNA splicing, amidases, polyadenylate binding heat shock, helix loop helix, HMG-box, CCAAT (HAP5), CRE-B histone acetyl transferases (MYST, SAGA) commonly expressed among natural plant biomass growth substrates. Further studies must be conducted to understand role involvement these degradation chrysosporium.

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