Impact of aortic stiffness on cardiovascular disease in patients with chest pain: assessment with direct intra-arterial measurement.
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DOI: 10.1016/J.AMJHYPER.2007.07.004
关键词: Chest pain 、 Medicine 、 Cardiology 、 Coronary artery disease 、 Odds ratio 、 Aortic stiffness 、 Internal medicine 、 Risk factor 、 Aorta 、 Heart failure 、 Univariate analysis
摘要: Background Aortic stiffness is an independent risk factor for cardiovascular (CV) events and mortality. However, there are few studies about the predictive role of aortic stiffness. We investigated association between pulse-wave velocity (aPWV), using direct intra-arterial measurement future CV events, in patients with chest pain. Methods was measured through aorto-femoral, fluid-filled system at baseline 1004 Among these patients, 497 (237 male) were enrolled study. examined tertiles. Tertiles defined as follows: tertile 1, 12.50 m/sec. The impact aPWV on newly developed coronary artery disease (CAD), stroke, congestive heart failure evaluated. Results A higher associated new (odds ratio, 2.18 3 v 1; 95% confidence interval [CI], 1.32 to 3.60) CAD 1.87 CI, 1.10 3.18) univariate analysis. In multivariate analysis, 2.05 1.18 3.55) 1.86 1.03 3.35). not either stroke ( P = .096) or .63). Conclusions These results suggest that
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Athanase Benetos, Michel Safar, Annie Rudnichi, Harold Smulyan, Jacques-Lucien Richard, Pierre Ducimetière, Louis Guize, Pulse Pressure A Predictor of Long-term Cardiovascular Mortality in a French Male Population Hypertension. ,vol. 30, pp. 1410- 1415 ,(1997) , 10.1161/01.HYP.30.6.1410
D. Leung, S Glagov, M. Mathews, Cyclic stretching stimulates synthesis of matrix components by arterial smooth muscle cells in vitro. Science. ,vol. 191, pp. 475- 477 ,(2003) , 10.1126/SCIENCE.128820
Roberto Sa Cunha, Bruno Pannier, Athanase Benetos, Jean-Philippe Siché, Gérard M. London, Jean Michel Mallion, Michel E. Safar, Association between high heart rate and high arterial rigidity in normotensive and hypertensive subjects. Journal of Hypertension. ,vol. 15, pp. 1423- 1430 ,(1997) , 10.1097/00004872-199715120-00009
S Madhavan, W L Ooi, H Cohen, M H Alderman, Relation of pulse pressure and blood pressure reduction to the incidence of myocardial infarction. Hypertension. ,vol. 23, pp. 395- 401 ,(1994) , 10.1161/01.HYP.23.3.395
Hideki Watanabe, Sadanori Ohtsuka, Masaaki Kakihana, Yasuro Sugishita, Coronary circulation in dogs with an experimental decrease in aortic compliance Journal of the American College of Cardiology. ,vol. 21, pp. 1497- 1506 ,(1993) , 10.1016/0735-1097(93)90330-4
Xavier Girerd, Stéphane Laurent, Bruno Pannier, Roland Asmar, Michel Safar, Arterial distensibility and left ventricular hypertrophy in patients with sustained essential hypertension American Heart Journal. ,vol. 122, pp. 1210- 1214 ,(1991) , 10.1016/0002-8703(91)90941-A
Claudia U Chae, Marc A Pfeffer, Robert J Glynn, Gary F Mitchell, James O Taylor, Charles H Hennekens, Increased pulse pressure and risk of heart failure in the elderly. JAMA. ,vol. 281, pp. 634- 643 ,(1999) , 10.1001/JAMA.281.7.634
X Girerd, M Safar, F Cambien, L Guize, B Darne, Pulsatile versus steady component of blood pressure: a cross-sectional analysis and a prospective analysis on cardiovascular mortality. Hypertension. ,vol. 13, pp. 392- 400 ,(1989) , 10.1161/01.HYP.13.4.392
Kennedy Cruickshank, Lisa Riste, Simon G. Anderson, John S. Wright, Graham Dunn, Ray G. Gosling, Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation. ,vol. 106, pp. 2085- 2090 ,(2002) , 10.1161/01.CIR.0000033824.02722.F7
D J Gordon, J L Probstfield, R J Garrison, J D Neaton, W P Castelli, J D Knoke, D R Jacobs, S Bangdiwala, H A Tyroler, High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation. ,vol. 79, pp. 8- 15 ,(1989) , 10.1161/01.CIR.79.1.8