cAMP signaling prevents podocyte apoptosis via activation of protein kinase A and mitochondrial fusion.
作者： Xiaoying Li , Hua Tao , Kewei Xie , Zhaohui Ni , Yucheng Yan
DOI: 10.1371/JOURNAL.PONE.0092003
关键词: Biology 、 Mitochondrion 、 mitochondrial fusion 、 Forskolin 、 Mitochondrial fission 、 Cell biology 、 Protein kinase A 、 Molecular biology 、 Podocyte 、 MFN1 、 Caspase 3
摘要: … ], [43] and PGC-1α expression is regulated by PKA, we think that PKA/PGC-1α signaling mediated forskolin-induced mitofusin-1 up-regulation. In fact, Cowell et al. found that mitofusin-…
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