Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites.

作者: Junzhe Zhang , Yuhui Ma , Wenjiang Yang , Jingquan Xue , Yayun Ding

DOI: 10.1039/C9NR00428A

关键词: Multimodal imagingNanoparticleNanotechnologyTheranostic NanomedicineIron oxideMaterials scienceNanocomposite

摘要: This work highlights the superiority of surface-radiolabeling strategy over core-labeling in assembly radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use multimodal imaging and targeted therapy. It also implies a possible overestimation labeling stability previous studies points out directions further optimization.

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