New trends in biological monitoring: application of biomarkers to genetic ecotoxicology

摘要: Environmental pollution is a complex issue because of the diversity anthropogenic agents, both chemical and physical, that have been detected catalogued. The consequences to biota from exposure genotoxic agents present an additional problem potential for these produce adverse change at cellular organismal levels. Organismal responses genetic level environmental genotoxicants well documented. Past studies in toxicology Oak Ridge National Laboratory focused on structural damage DNA species may occur after use this information document monitor remediation. Current ecotoxicology are attempting characterize biological mechanisms gene regulate limit response individual organism factors their environment. An elucidation molecular involved with responses, as assessment changes material, will provide understanding deleterious higher levels organization. Moreover, modern procedures biology offer hope alterations material can be readily detected.