Correlation between sarcopenia and albuminuria in patients with type 2 diabetes
作者： Chun Liu , Kaiyuan Zheng , Chuan Lin , Junfeng Yan
DOI: 10.12122/J.ISSN.1673-4254.2020.03.20
关键词: Renal function 、 Albuminuria 、 Sarcopenia 、 Creatinine 、 Kidney disease 、 Blood pressure 、 Urology 、 Type 2 diabetes 、 Medicine 、 Lean body mass
摘要: Objective To investigate the correlation between sarcopenia and albuminuria in patients with type 2 diabetes mellitus (T2DM). Methods A total of 360 T2DM (including 206 male 154 female patients) hospitalized our hospital January, 2015 December, 2018 were enrolled. According to their medical history laboratory test results, divided into group (n=122) non-albuminuria (n=238). The clinical anthropological data collected skeletal muscle index (SMI), appendage lean mass, index, body fat, bone mineral capacity density measured using dual-energy X-ray absorptiometry. Logistic regression was used analyze these composition parameters or chronic kidney disease (CKD) diabetic patients. Results course T2DM, hypertension, age, systolic blood pressure, low lipoprotein cholesterol, triglyceride, uric acid, waistline, Urinary albumin creatinine ratio, serum creatinine, glomerular filtration rate differed significantly those without (P 0.05). Conclusions Sarcopenia is probably an independent risk factor for T2DM.
sci-hub.st 参考文章(31)
B Feldt-Rasmussen, Microalbuminuria, endothelial dysfunction and cardiovascular risk. Diabetes & Metabolism. ,vol. 26, pp. 64- 66 ,(2000)
Sung Jin Moon, Tae Ho Kim, Soo Young Yoon, Jae Ho Chung, Hee-Jin Hwang, Relationship between Stage of Chronic Kidney Disease and Sarcopenia in Korean Aged 40 Years and Older Using the Korea National Health and Nutrition Examination Surveys (KNHANES IV-2, 3, and V-1, 2), 2008–2011 PLOS ONE. ,vol. 10, pp. e0130740- ,(2015) , 10.1371/JOURNAL.PONE.0130740
Seong-Su Moon, Low skeletal muscle mass is associated with insulin resistance, diabetes, and metabolic syndrome in the Korean population: The Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010 Endocrine Journal. ,vol. 61, pp. 61- 70 ,(2014) , 10.1507/ENDOCRJ.EJ13-0244
Robert N. Foley, Changchun Wang, Areef Ishani, Allan J. Collins, Anne M. Murray, Kidney function and sarcopenia in the United States general population: NHANES III. American Journal of Nephrology. ,vol. 27, pp. 279- 286 ,(2007) , 10.1159/000101827
A.J. O'Sullivan, J.J. Kelly, Insulin resistance and protein catabolism in non-diabetic hemodialysis patients Kidney International. ,vol. 71, pp. 98- 100 ,(2007) , 10.1038/SJ.KI.5002045
K.L. Timmerman, E. Volpi, Endothelial function and the regulation of muscle protein anabolism in older adults Nutrition Metabolism and Cardiovascular Diseases. ,vol. 23, ,(2013) , 10.1016/J.NUMECD.2012.03.013
A. Rashid Qureshi, Anders Alvestrand, Anders Danielsson, José C. Divino-Filho, Alberto Gutierrez, Bengt Lindholm, Jonas Bergström, Factors predicting malnutrition in hemodialysis patients: A cross-sectional study Kidney International. ,vol. 53, pp. 773- 782 ,(1998) , 10.1046/J.1523-1755.1998.00812.X
D. Power, Standards of Medical Care in Diabetes: Response to position statement of the American Diabetes Association Diabetes Care. ,vol. 29, pp. 476- 476 ,(2006) , 10.2337/DIACARE.29.02.06.DC05-1593
Per-Henrik Groop, Carol Forsblom, Merlin C Thomas, Mechanisms of disease: Pathway-selective insulin resistance and microvascular complications of diabetes. Nature Clinical Practice Endocrinology & Metabolism. ,vol. 1, pp. 100- 110 ,(2005) , 10.1038/NCPENDMET0046
Lara B. Pupim, Olof Heimburger, Abdul Rashid Qureshi, T. A.L.P. Ikizler, Peter Stenvinkel, Accelerated lean body mass loss in incident chronic dialysis patients with diabetes mellitus Kidney International. ,vol. 68, pp. 2368- 2374 ,(2005) , 10.1111/J.1523-1755.2005.00699.X