1H Nuclear Magnetic Resonance Metabolomics Analysis Identifies Novel Urinary Biomarkers for Lung Function
作者： Joseph L. McClay , Daniel E. Adkins , Nancy G. Isern , Thomas M. O’Connell , Jan B. Wooten
DOI: 10.1021/PR1000048
关键词: Creatinine 、 Toxicology 、 Urinary system 、 Metabolite 、 Lung 、 Metabolomics 、 Biomarker (medicine) 、 Chemistry 、 Urine 、 COPD 、 Internal medicine 、 Gastroenterology
摘要: … In this study, we used proton nuclear magnetic resonance ( 1 H NMR) spectroscopy to identify … metabolomics as a screening tool for identifying novel biomarkers of pulmonary outcomes. …
acs.org
sci-hub.se 参考文章(49)
Daniel Melnick, William D. Robinson, Henry Field, URINARY EXCRETION OF NICOTINIC ACID AND ITS DERIVATIVES BY NORMAL INDIVIDUALS Journal of Biological Chemistry. ,vol. 136, pp. 145- 156 ,(1940) , 10.1016/S0021-9258(18)73087-1
Jeremy K. Nicholson, Elaine Holmes, Ian D. Wilson, Gut microorganisms, mammalian metabolism and personalized health care Nature Reviews Microbiology. ,vol. 3, pp. 431- 438 ,(2005) , 10.1038/NRMICRO1152
TALITHA L. FEENSTRA, MARIANNE L. L. van GENUGTEN, RUDOLF T. HOOGENVEEN, EMIEL F. WOUTERS, MAUREEN P. M. H. RUTTEN-van MÖLKEN, The impact of aging and smoking on the future burden of chronic obstructive pulmonary disease: a model analysis in the Netherlands. American Journal of Respiratory and Critical Care Medicine. ,vol. 164, pp. 590- 596 ,(2001) , 10.1164/AJRCCM.164.4.2003167
J. D. Storey, R. Tibshirani, Statistical significance for genomewide studies Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 9440- 9445 ,(2003) , 10.1073/PNAS.1530509100
B LUNDBÄCK, A LINDBERG, M LINDSTRÖM, E RÖNMARK, A.C JONSSON, E JÖNSSON, L.-G LARSSON, S ANDERSSON, T SANDSTRÖM, K LARSSON, Not 15 But 50% of smokers develop COPD?- : Report from the Obstructive Lung Disease in Northern Sweden Studies Respiratory Medicine. ,vol. 97, pp. 115- 122 ,(2003) , 10.1053/RMED.2003.1446
J.R. Hoidal, Genetics of COPD: present and future European Respiratory Journal. ,vol. 18, pp. 741- 743 ,(2001) , 10.1183/09031936.01.00268501
Huiru Tang, Yulan Wang, Jeremy K. Nicholson, John C. Lindon, Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma. Analytical Biochemistry. ,vol. 325, pp. 260- 272 ,(2004) , 10.1016/J.AB.2003.10.033
Roman Lang, Erkan Firat Yagar, Rudolf Eggers, Thomas Hofmann, Quantitative investigation of trigonelline, nicotinic acid, and nicotinamide in foods, urine, and plasma by means of LC-MS/MS and stable isotope dilution analysis. Journal of Agricultural and Food Chemistry. ,vol. 56, pp. 11114- 11121 ,(2008) , 10.1021/JF802838S
John E. Connett, John W. Kusek, William C. Bailey, Peggy O'Hara, Margaret Wu, Design of the Lung Health Study: A randomized clinical trial of early intervention for chronic obstructive pulmonary disease Controlled Clinical Trials. ,vol. 14, pp. 3- 19 ,(1993) , 10.1016/0197-2456(93)90021-5
D. M. Mannino, S. Braman, The epidemiology and economics of chronic obstructive pulmonary disease Proceedings of the American Thoracic Society. ,vol. 4, pp. 502- 506 ,(2007) , 10.1513/PATS.200701-001FM