Coated pits act as molecular filters.

作者： M. S. Bretscher , J. N. Thomson , B. M. Pearse

关键词: Membrane 、 Membrane lipids 、 Chemistry 、 Coated Pit 、 Membrane protein 、 Biological membrane 、 Peripheral membrane protein 、 Cell biology 、 Biophysics 、 Cell membrane 、 Membrane fluidity

摘要: Abstract Two proteins--theta and H63 antigens--are found to be excluded from coated pits on fibroblast plasma membranes. Coated thus act as molecular filters, pinching off, into the cell, lipid vesicles containing a limited number of specific receptors but excluding other membrane proteins. This constitutes part flow cycle that was proposed earlier explain capping crosslinked surface antigens.