Apoptosis signal-regulating kinase 1 as a therapeutic target.

作者: Yosuke Kawarazaki , Hidenori Ichijo , Isao Naguro

DOI: 10.1517/14728222.2014.896903

关键词: KinaseOxidative stressCellular stress responseASK1BioinformaticsDiseaseBiologyEndoplasmic reticulumHomeostasisCell biologyReactive oxygen species

摘要: … Apoptosis signal-regulating kinase 1 (ASK1) is one of the stress-responsive MAP3Ks. ASK1 plays an important role in the response to reactive oxygen species (ROS), endoplasmic …

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