Horizons and Group Motivational Enhancement Therapy: HIV Prevention for Alcohol-Using Young Black Women, a Randomized Experiment

摘要: Introduction Black women are at disproportionately greater risk for HIV and sexually transmitted infections than of other ethnic/racial backgrounds. Alcohol use may further elevate the HIV/sexually infection acquisition transmission. Study Design A random-assignment parallel-group comparative treatment efficacy trial was conducted with random assignment to 1 3 conditions.z Setting/participants The sample comprised 560 or African American aged 18–24 years who reported recent unprotected vaginal anal sex alcohol use. Participants were recruited from community settings in Atlanta, Georgia, January 2012 February 2014. Intervention Group Motivational Enhancement Therapy module designed complement a Centers Disease Control Prevention–designated evidenced-based intervention (Horizons) reduce sexual behaviors, use, infections, comparison groups: (1) Horizons + Group intervention, (2) Horizons + General Health Promotion (3) enhanced standard care. Main outcome measures Outcome included safe (abstinence 100% condom use); nonuse; proportion during episodes; incident chlamydia, gonorrhea, trichomonas infections; problematic measured by Use Disorders Identification Test score. Treatment effects estimated using an intention-to-treat protocol‒generalized estimating equations logistic regression binomial outcomes Poisson count outcomes. Analyses between October 2018 2019. Results assigned had odds (AOR=1.45, 95% CI=1.04, 2.02, p=0.03), (AOR=1.68, CI=1.18, 2.41, p=0.004), lower nonuse (AOR=0.57, CI=0.38, 0.83, p=0.004). Both interventions (Horizons: AOR=0.57, CI=0.39, 0.85, p=0.006; Therapy: AOR=0.61, CI=0.41, 0.90, p=0.01). Conclusions Complementing evidence-based prevention increase safer behaviors concomitantly among young consume alcohol. Trial registration This study is registered www.clinicaltrials.gov NCT01553682.