Molecular imaging in animal models of disease--every little detail counts!

B. Munch-Petersen, L. Cloos, G. Tyrsted, S. Eriksson, Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. Journal of Biological Chemistry. ,vol. 266, pp. 9032- 9038 ,(1991) , 10.1016/S0021-9258(18)31547-3

Anthony F. Shields, John R. Grierson, Bernhard M. Dohmen, H.-Juergen Machulla, Joseph C. Stayanoff, Jawana M. Lawhorn-Crews, Joyce E. Obradovich, Otto Muzik, Thomas J. Mangner, Imaging proliferation in vivo with [F-18]FLT and positron emission tomography. Nature Medicine. ,vol. 4, pp. 1334- 1336 ,(1998) , 10.1038/3337

X B Kong, Q Y Zhu, P M Vidal, K A Watanabe, B Polsky, D Armstrong, M Ostrander, S A Lang, E Muchmore, T C Chou, Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine. Antimicrobial Agents and Chemotherapy. ,vol. 36, pp. 808- 818 ,(1992) , 10.1128/AAC.36.4.808

J. L. Pauly, M. G. Schuller, A. A. Zelcer, M. J. Germain, Degradation of [3H]thymidine by a pentosyltransferase (EC 2.4.2.4) in the plasma of man and different animals. Cellular and Molecular Life Sciences. ,vol. 33, pp. 668- 670 ,(1977) , 10.1007/BF01946565

Henryk Barthel, Meg Perumal, John Latigo, Qimin He, Frank Brady, Sajinder K. Luthra, Pat M. Price, Eric O. Aboagye, The uptake of 3′-deoxy-3′-[ 18 F]fluorothymidine into L5178Y tumours in vivo is dependent on thymidine kinase 1 protein levels European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 32, pp. 257- 263 ,(2005) , 10.1007/S00259-004-1611-0

Aren van Waarde, Albert J H Suurmeijer, Harald J Hoekstra, David C P Cobben, Erik F J de Vries, Bram Maas, Pieter L Jager, Philip H Elsinga, Willem Vaalburg, Selectivity of 18F-FLT and 18F-FDG for Differentiating Tumor from Inflammation in a Rodent Model The Journal of Nuclear Medicine. ,vol. 45, pp. 695- 700 ,(2004)