RNA metabolism and regulation of virulence programs in fungi.

作者: Ane Sesma

DOI: 10.1016/J.SEMCDB.2016.03.019

关键词: GeneticsRNA splicingRNAVirulenceHuman pathogenBiologyFunction (biology)Post-transcriptional regulationTranslation (biology)Systems biology

摘要: The development of RNA imaging techniques and the establishment systems biology approaches, together with improvement large-scale RNA-protein crosslinking immunoprecipitation protocols have enormously expanded our knowledge networks function RNA-binding proteins in metazoans model yeasts. In pathogenic fungi, biological role vast majority non-coding RNAs is still largely unknown. However, many RNA-dependent mechanisms which shape fungal pathogenicity been defined. Here, advances made this field are reviewed further theories significance discussed light latest findings.

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