Cardiac Actions of Protein Kinase C Isoforms
DOI: 10.1152/PHYSIOL.00009.2012
关键词: MAP kinase kinase kinase 、 Mitogen-activated protein kinase kinase 、 Protein kinase C 、 PKC alpha 、 Endocrinology 、 Internal medicine 、 Cell biology 、 Biology 、 ASK1 、 Ca2+/calmodulin-dependent protein kinase 、 PRKCE 、 MAP2K7
摘要: Protein kinase C (PKC) isoforms have emerged as important regulators of cardiac contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury. This review focuses on newer concepts regarding PKC isoform-specific activation mechanisms actions implications for the development PKC-targeted therapeutics.
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