Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor.
作者： B Savage , S.J. Shattil , Z.M. Ruggeri
DOI: 10.1016/S0021-9258(19)49910-9
关键词: Glycoprotein IIb/IIIa 、 Cell adhesion 、 Chemistry 、 Platelet membrane glycoprotein 、 Biochemistry 、 Platelet 、 Integrin 、 Platelet activation 、 Molecular biology 、 Integrin Alpha-IIb/Beta-3 、 Glycoprotein Ib
摘要: … We have found that the form of glycoprotein (GP) IIb-IIIa (integrin alpha IIb beta 3) expressed on nonstimulated platelets is a functional receptor that mediates selective and irreversible …
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