Optimization of breast cancer detection in Dual Energy X-ray Mammography using a CMOS imaging detector

摘要: Dual energy mammography has the ability to improve detection of microcalcifications leading early diagnosis breast cancer. In this simulation study, a prototype dual system, using CMOS based imaging detector with different X-ray spectra, was modeled. The device consists 33.91 mg/cm2 Gd2O2S:Tb scintillator screen, placed in direct contact sensor, pixel size 22.5 μm. Various filter materials and tube voltages Tungsten (W) anode for both low high were examined. selection filters applied W spectra on their K- edges (K-edge filtering). Hydroxyapatite (HAp) used simulate microcalcifications. Calcification signal-to-noise ratio (SNRtc) calculated entrance surface dose within acceptable levels conventional mammography. Optimization maximization SNRtc while minimizing dose. best compromise between value provided by 35kVp spectrum added beam filtration 100μm Pd 70kVp Yb filtered 800 μm energy, respectively. Computer results show that 3.6 can be achieved calcification 200 Compared previous studies, method detectability