Mechanisms mediating renal sympathetic nerve activation in obesity-related hypertension
作者： W. Chen , S. Leo , C. Weng , X. Yang , Y. Wu
DOI: 10.1007/S00059-014-4072-7
关键词: Endocrinology 、 Rostral ventrolateral medulla 、 Baroreflex 、 Hyperinsulinemia 、 Denervation 、 Renal sympathetic denervation 、 Medicine 、 Blood pressure 、 Adipokine 、 Pathophysiology of hypertension 、 Internal medicine
摘要: Excessive renal sympathetic nerve activation may be one of the mechanisms underlying obesity-related hypertension. Impaired baroreflex sensitivity, adipokine disorders—such as leptin, adiponectin, and resistin—activation renin-angiotensin system, hyperinsulinemia, insulin resistance, sodium retention present in obesity increase activity, thus contributing to development Renal denervation reduces both activity blood pressure patients with
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