Redox and pH Dual Responsive Polymer Based Nanoparticles for In Vivo Drug Delivery

作者: Chung Yen Ang , Si Yu Tan , Cathleen Teh , Jia Min Lee , Mun Fei Eddy Wong

DOI: 10.1002/SMLL.201602379

关键词: Drug deliveryCancer cellPharmacologyBiophysicsMaterials scienceDrugNanomaterialsDoxorubicinIn vitroNanoparticleIn vivo

摘要: … Confocal imaging is utilized to provide the daily assessment of tumor size on … nanoparticles with dual responsive properties for both in vitro and in vivo drug delivery in the cancer therapy…

参考文章(45)
Wei Chen, Fenghua Meng, Ru Cheng, Chao Deng, Jan Feijen, Zhiyuan Zhong, Facile construction of dual-bioresponsive biodegradable micelles with superior extracellular stability and activated intracellular drug release Journal of Controlled Release. ,vol. 210, pp. 125- 133 ,(2015) , 10.1016/J.JCONREL.2015.05.273
Dong Youl Cho, Hana Cho, Kiyoon Kwon, Minjong Yu, Eunji Lee, Kang Moo Huh, Don Haeng Lee, Han Chang Kang, Triphenylphosphonium‐Conjugated Poly(ε‐caprolactone)‐Based Self‐Assembled Nanostructures as Nanosized Drugs and Drug Delivery Carriers for Mitochondria‐Targeting Synergistic Anticancer Drug Delivery Advanced Functional Materials. ,vol. 25, pp. 5479- 5491 ,(2015) , 10.1002/ADFM.201501422
Chung Yen Ang, Si Yu Tan, Shaojue Wu, Qiuyu Qu, Mun Fei Eddy Wong, Zhong Luo, Pei-Zhou Li, Subramanian Tamil Selvan, Yanli Zhao, A dual responsive “turn-on” fluorophore for orthogonal selective sensing of biological thiols and hydrogen peroxide Journal of Materials Chemistry C. ,vol. 4, pp. 2761- 2774 ,(2016) , 10.1039/C5TC01465D
Scott H. Medina, Mohamed E. H. El-Sayed, Dendrimers as carriers for delivery of chemotherapeutic agents. Chemical Reviews. ,vol. 109, pp. 3141- 3157 ,(2009) , 10.1021/CR900174J
Mahmoud Elsabahy, Karen L. Wooley, Design of polymeric nanoparticles for biomedical delivery applications Chemical Society Reviews. ,vol. 41, pp. 2545- 2561 ,(2012) , 10.1039/C2CS15327K
T Volk, E Jähde, HP Fortmeyer, K-H Glüsenkamp, MF Rajewsky, pH in human tumour xenografts: effect of intravenous administration of glucose. British Journal of Cancer. ,vol. 68, pp. 492- 500 ,(1993) , 10.1038/BJC.1993.375
Alberto Gabizon, Hilary Shmeeda, Aviva T Horowitz, Samuel Zalipsky, Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates. Advanced Drug Delivery Reviews. ,vol. 56, pp. 1177- 1192 ,(2004) , 10.1016/J.ADDR.2004.01.011
Mauro Ferrari, Cancer nanotechnology: opportunities and challenges Nature Reviews Cancer. ,vol. 5, pp. 161- 171 ,(2005) , 10.1038/NRC1566
Yechezkel (Chezy) Barenholz, Doxil®--the first FDA-approved nano-drug: lessons learned. Journal of Controlled Release. ,vol. 160, pp. 117- 134 ,(2012) , 10.1016/J.JCONREL.2012.03.020
Scott K. Parks, Johanna Chiche, Jacques Pouyssegur, pH control mechanisms of tumor survival and growth Journal of Cellular Physiology. ,vol. 226, pp. 299- 308 ,(2011) , 10.1002/JCP.22400