Biochemical markers of bone turnover – uses and limitations
作者： Thinn Thinn Hlaing , Juliet E Compston
关键词: Bone markers 、 Osteoporosis 、 Bioinformatics 、 Bone marker 、 Medicine 、 Bone mineral 、 Pathology 、 Biochemical markers 、 Medical laboratory 、 Bone remodeling 、 Clinical Practice
摘要: Bone turnover markers of resorption and formation are released during the process bone remodelling. These have been extensively studied in a number therapeutic trials osteoporosis past decade. This has led to better understanding their physiology, clinical applications possible ways optimize analytical techniques. can complement results mineral density management osteoporosis, but use practice is challenged by pre-analytical variability. review will discuss different types markers, limitations, metabolic diseases current recommendations from International Osteoporosis Foundation Federation Clinical Chemistry Laboratory Medicine marker standards working group.
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