Synthesis and in vitro antitumour activities of lupeol derivatives.
作者： Weijie Li , Yeyu Xiao
DOI: 10.1080/14786419.2017.1329729
关键词: Liver cancer 、 Chemistry 、 In vitro 、 A549 cell 、 Biochemistry 、 Lupeol 、 Hepg2 cells
摘要: Nine lupeol derivatives were synthesised and assayed in vitro for their antitumour activities against three human tumour cells lines, A549, LAC HepG2. Of derivaties, six new compounds, five compounds A549 cells, four HepG2 cells were effective reducing viability, the most promising 5, 6 9 exhibited high lung liver cancer even higher than those of adriamycin.
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