Comparative Effectiveness of Unruptured Cerebral Aneurysm Therapies
作者： Jennifer S. McDonald , Robert J. McDonald , Jiaquan Fan , David F. Kallmes , Giuseppe Lanzino
DOI: 10.1161/STROKEAHA.111.000196
关键词: Unruptured cerebral aneurysm 、 Propensity score matching 、 Comparative effectiveness research 、 Surgery 、 Conditional logistic regression 、 Clipping (medicine) 、 Aneurysm 、 Matching methods 、 Unruptured aneurysm 、 Medicine 、 Advanced and Specialised Nursing 、 Clinical neurology 、 Cardiology and Cardiovascular Medicine
摘要: Background and Purpose—Endovascular therapy has increasingly become the most common treatment for unruptured cerebral aneurysms in United States. We evaluated a national, multi-hospital database to examine recent utilization trends compare periprocedural outcomes between clipping coiling treatments of aneurysms. Methods—The Premier Perspective was used identify patients hospitalized 2006 2011 aneurysm who underwent or therapy. A logistic propensity score generated each patient using relevant patient, procedure, hospital variables, representing probability receiving clipping. Covariate balance assessed conditional regression. Following adjustment 1:1 matching methods, risk in-hospital mortality morbidity compared cohorts. Results—A total 4899 (1388 clipping, 3551 coiling) treated at 120...
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