Pharmacokinetics of exogenous adenosine in man after infusion

作者: P. Blardi , F. Laghi Pasini , R. Urso , C. Frigerio , L. Volpi

DOI: 10.1007/BF00315554

关键词: AnesthesiaPlasma kineticsHalf-lifePharmacologyAdenosineHealthy volunteersMetabolic clearance ratePharmacology toxicologyVolunteerMedicinePharmacokinetics

摘要: The plasma kinetics of adenosine was investigated in healthy volunteers after a 1 minute infusion 2.5, 5 and 10 mg (38, 79 148 μg·kg−1 respectively) 200 min followed by 400 min.

参考文章(4)
Richard E. Klabunde, Dipyridamole inhibition of adenosine metabolism in human blood. European Journal of Pharmacology. ,vol. 93, pp. 21- 26 ,(1983) , 10.1016/0014-2999(83)90026-2
G. H. Moser, J. Schrader, A. Deussen, Turnover of adenosine in plasma of human and dog blood. American Journal of Physiology-cell Physiology. ,vol. 256, ,(1989) , 10.1152/AJPCELL.1989.256.4.C799
Anders Edlund, Alf Sollevi, Birgitta Linde, Haemodynamic and metabolic effects of infused adenosine in man. Clinical Science. ,vol. 79, pp. 131- 138 ,(1990) , 10.1042/CS0790131