Changing demographics of cervical cancer in the United States (1973-2008).

摘要: Abstract Objective To describe changes in the cervical cancer population. Methods The SEER database 9 registries from 1973 to 2008 were queried perform a retrospective cohort study of women with invasive cancer. Estimated annual percent change (EAPC) incidence rates and 95% confidence intervals (CI) over entire period compared according age, stage, race, cell type (squamous [SCC] adenocarcinoma [ACA]). Proportions odds ratios (OR) calculated for patients diagnosed during second half (1990–2008) first (1973–89) period. Results 40,363 entered into SEER. EAPC are falling fastest among those localized disease (−2.5%; CI −2.8 −2.1), age≥50 (−3.0%; CI=−3.2 −2.8), black (−3.8%; CI=−4.1 −3.6). newly patient having advanced 10% higher, being less than age 50 37% Asian or Pacific Islander 68% higher time as first. Conclusions In US, population is changing. Patients presently significantly more likely be pre-menopausal, Islander, frequently have non-squamous histology previously. These progressive cumulative could due disparate impact current based screening prevention strategies. Understanding implications these evolving characteristics may facilitate planning targeted studies interventions prevention, treatment future.