Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements.
作者： Maria Suciu , Corina M Ionescu , Alexandra Ciorita , Septimiu C Tripon , Dragos Nica
DOI: 10.3762/BJNANO.11.94
关键词: Nanotechnology 、 Drug 、 Safety studies 、 Ex vivo 、 In vivo 、 Drug delivery 、 Context (language use) 、 Superparamagnetic iron oxide nanoparticles 、 Targeted drug delivery 、 Chemistry
摘要: Superparamagnetic iron oxide nanoparticles (SPIONs) have unique properties with regard to biological and medical applications. SPIONs been used in clinical settings although their safety of use remains unclear due the great differences structure intra- inter-patient absorption response. This review addresses potential applications vitro (formulations), ex vivo (in cells tissues) (preclinical animal models), as well biomedical context drug targeting, disease treatment therapeutic efficacy, studies.
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