Bromocriptine in Parkinsonism.

摘要: Bromocriptine, a drug acting directly upon dopaminergic receptors, has been found to have significant therapeutic action in double-blind study of 20 patients with idiopathic Parkinsonism who were already receiving conventional therapy, including levodopa. Neurological deficits improved by almost 20% severely disabled patients; amelioration mildly affected was about 10%. Adverse reactions similar those encountered levodopa—they all dose-dependent and reversible. These observations are discussed relation certain theoretical advantages which might be expected from acts on receptors.