Acute liver failure: established and putative hepatitis viruses and therapeutic implications.

作者: Roger Williams , Stephen M Riordan

DOI: 10.1046/J.1440-1746.2000.02260.X

关键词: ImmunologyHepatitis BViral hepatitisLiver transplantationMedicineViral diseaseHepatitis C virusHepatitisVirusHepatitis CVirology

摘要: Any virus that can cause an acute hepatitis will, on occasion, give rise to liver failure. Such infections be separated into those due the primary viral A E and where occurs as part of a systemic infection, with infection with, for instance, Epstein-Barr virus, cytomegalovirus, Varicella zoster adenovirus Herpes simplex virus. In general, frequency which different viruses are responsible failure is related their underlying prevalence in particular countries. An apparent exception striking geographical variation reported C much higher proportion cases generally attributed this agent Japan Taiwan than Western Recent work has focused possible importance mutant B strains, co- super-infection known certain newly described agents may account otherwise unexplained Despite improved understanding pathogenesis complicating cerebral oedema advances general supportive care, it likely most severely affected patients causes will survive only transplantation, at least until approaches promoting adequate regeneration successfully developed implemented.

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