Comparative Analysis of Mutant Tyrosine Kinase Chemical Rescue
作者： Kathryn E. Muratore , Markus A. Seeliger , Zhihong Wang , Dina Fomina , Johnathan Neiswinger
DOI: 10.1021/BI900057G
关键词: Biology 、 SH2 domain 、 SH3 domain 、 Receptor tyrosine kinase 、 Proto-Oncogene Proteins c-abl 、 Biochemistry 、 Proto-oncogene tyrosine-protein kinase Src 、 Tyrosine-protein kinase CSK 、 Tyrosine kinase 、 Protein tyrosine phosphatase
摘要: Protein tyrosine kinases are critical cell signaling enzymes. These enzymes have a highly conserved Arg residue in their catalytic loop which is present two residues or four downstream fro...
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