作者: Masahiro Iwamoto , Katsuhiko Sato , Kazuhisa Nakashima , Hajime Fuchihata , Fujio Suzuki
DOI: 10.1016/0006-291X(89)92208-0
关键词: Cell culture 、 Internal medicine 、 Chondrocyte 、 Cell growth 、 Fibroblast growth factor 、 Transforming growth factor 、 Endocrinology 、 Biology 、 Cartilage 、 Cell biology 、 Transforming growth factor beta 、 Cell
摘要: Abstract Fibroblast growth factor (FGF) induces colony formation by chondrocytes in soft agar (Y. Kato et al., J. Cell. Physiol., 1987), and the present study revealed that transforming factor-beta (TGF-beta) does not induce same effect. TGF-beta did, however, increase efficiency of 3- to 4-fold presence a maximal dose FGF. Furthermore, decreased concentrations FGF needed for induction cell 40- 100-fold. These results suggest is involved control cartilage possibly increasing responsiveness