What’s All the Fuss About? Facts and Figures About Bone Marrow Failure and Conditions

摘要: The epidemiology of bone marrow failure conditions is not well understood. Although several population-based studies conducted in the last two decades have generated a wealth information, it still very challenging to interpret disease incidence and prevalence, particularly due changes classification, misdiagnosis patients, frequent underreporting use different referent populations calculate rates. Despite these limitations, available epidemiologic data revealed significant ethnic, geographic clinical differences biology that implications for prevention treatment strategies. With advances made targeted therapies facilitated by identification molecular biomarkers increased curative transplantation approach, natural history entities already changing. diseases seems be next frontier as knowledge gained about risk factors pathobiologic correlates could significantly help designing patient-specific with improved outcomes.