Pain disaggregation theory—statistical nonsense or a pointer to a paradigm for quantum nociception?

作者: I.D. Conacher , G. Sudarshan , A.K. Soni

DOI: 10.1093/BJA/AEG153

关键词: Rating scoreOutcome measuresAnalgesicIntercostal nervesPhysical therapyMedicineProspective cohort studyNociceptionConstruct (philosophy)Pain relief

摘要: Background The various patterns of patients’ experience treated acute post-thoracotomy pain exemplify the phenomenon disaggregation. intent in this study was to define a theory disaggregation with hard-wired neuroanatomical model thoracotomy pain. Methods In order distinguish disaggregated nociception conducted along one three possible pathways, vagus, phrenic and, study, intercostal nerves, data from 143 patients undergoing thoracic surgery, and that two previously studies multimodal analgesic regimens, were reviewed. values subjective outcome measure (verbal rating score) at different stress levels—at rest, on raising arm, coughing (dynamic scores)—were used construct individuals’ charts (pain profiles) progress relief over time. These batched, analysed using statistics summary measures. Results This crude exercise handling redundant data, but there is suggestion it route by an effect treatment mass nociception. Conclusions information could underpin paradigm quantum nociception, has potential quantify aspects analgesia practice current future neurophysiological theories Prospective are warranted.

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