Gastric carcinoma: Evaluation with diffusion-tensor MR imaging and tractography ex vivo

摘要: Abstract Purpose To determine the feasibility of diffusion-tensor imaging (DTI) and tractography as means evaluating depth mural invasion by gastric carcinomas. Materials methods This study was approved our institutional review board, written informed consent obtained from each patient. Twenty specimens containing a carcinoma were studied with 7.0-T MR system equipped four-channel phased-array surface coil. DTI performed using field view 50–60 mm × 25–30 mm, matrix 256 × 128, section thickness 1 mm, b value 1000 s/mm2, motion-probing gradients in seven noncollinear directions. The images compared histopathologic findings reference standard. Results In all 20 carcinomas (100%) diffusion-weighted images, apparent diffusion coefficient (ADC) maps, fractional anisotropy (FA) λ1 direction-encoded color FA maps made it possible to identify same tumor wall observed during examination. provided best contrast between layers wall. also had lower ADC values than normal wall; thus, clearly demarcated Tractography useful for determining Conclusions are feasible provide excellent diagnostic accuracy