Clinical, demographic, and laboratory characteristics of children with nephrolithiasis

作者: David J. Sas , Lauren J. Becton , Jeffrey Tutman , Laura A. Lindsay , Amy H. Wahlquist

DOI: 10.1007/S00240-015-0827-8

关键词: NephrologyKidney stonesRisk factorPediatricsBody mass indexIncidence (epidemiology)PopulationStatistical significanceHypercalciuriaInternal medicineMedicine

摘要: While the incidence of pediatric kidney stones appears to be increasing, little is known about demographic, clinical, laboratory, imaging, and management variables in this patient population. We sought describe various characteristics our stone-forming To that end, we retrospectively reviewed charts patients with nephrolithiasis confirmed by imaging. Data were collected on multiple from each analyzed for trends. For body mass index (BMI) controls, data general pediatrics population similar used. 155 analyzed. Of 54 calculi available analysis, 98 % calcium based. Low urine volume, elevated supersaturation phosphate, oxalate, hypercalciuria most commonly identified abnormalities analysis 24-h collections. Our did not have a higher BMI than population, making it unlikely obesity risk factor children. More girls presented their first stone during adolescence, suggesting role reproductive hormones contributing risk, while boys tended present more at younger age, though reach statistical significance. These intriguing findings warrant further investigation.

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