Sperm viral infection and male infertility: focus on HBV, HCV, HIV, HPV, HSV, HCMV, and AAV.

摘要: a b s t r c Chronic viral infections can infect sperm and are considered risk factor in male infertility. Recent studies have shown that the presence of HIV, HBV or HCV semen impairs parameters, DNA integrity, particular reduces forward motility. In contrast, very little is known about infection with human papillomaviruses (HPV), herpesviruses (HSV), cytomegalovirus (HCMV), adeno-associated virus (AAV). At present, EU directives for screening couples undergoing assisted reproduction techniques require only evaluation HBV, HCV. However, growing evidence suggests HPV, HSV, HCMV might play major role infertility it has been demonstrated HPV negative influence on fertilization, abortion rate. Besides horizontal vertical transmission, impact any reproductive function seems to be dramatic. addition, treatment antiviral antiretroviral therapies may further affect parameters. this review we attempted focus interactions between defined their association fertility disorders. All viruses article potentially effect dangerous transmitted partners newborns. light evidence, suggest performing targeted washing procedures each strongly consider patients seeking HCMV, both avoid transmission improve even spontaneous outcome.