Stabilization of i-motif structures by 2′-β-fluorination of DNA

作者: Hala Abou Assi , Robert W. Harkness , Nerea Martin-Pintado , Christopher J. Wilds , Ramón Campos-Olivas

DOI: 10.1093/NAR/GKW402

关键词: OligonucleotideDNANuclear magnetic resonance spectroscopyBiologyBiochemistryCytosineConformational changeCrystallographyBase pairIntercalation (chemistry)Macromolecule

摘要: i-Motifs are four-stranded DNA structures consisting of two parallel DNA duplexes held together by hemi-protonated and intercalated cytosine base pairs (C:CH + ). They have attracted …

参考文章(61)
Aaron L. Moye, Karina C. Porter, Scott B. Cohen, Tram Phan, Katherine G. Zyner, Natsuki Sasaki, George O. Lovrecz, Jennifer L. Beck, Tracy M. Bryan, Telomeric G-quadruplexes are a substrate and site of localization for human telomerase Nature Communications. ,vol. 6, pp. 7643- 7643 ,(2015) , 10.1038/NCOMMS8643
S. Gordon Rule, T. Kevin Hitchens, Fundamentals of protein NMR spectroscopy Fundamentals of Protein NMR Spectroscopy. pp. 1- 4020 ,(2006)
Sonia Pérez-Rentero, Raimundo Gargallo, Carlos González, Ramon Eritja, Modulation of the stability of i-motif structures using an acyclic threoninol cytidine derivative RSC Advances. ,vol. 5, pp. 63278- 63281 ,(2015) , 10.1039/C5RA10096H
Joana Fraga, Ana Maranha, Vitor Mendes, Pedro José Barbosa Pereira, Nuno Empadinhas, Sandra Macedo-Ribeiro, None, Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway Scientific Reports. ,vol. 5, pp. 8026- 8026 ,(2015) , 10.1038/SREP08026
Yuanchen Dong, Zhongqiang Yang, Dongsheng Liu, DNA Nanotechnology Based on i-Motif Structures Accounts of Chemical Research. ,vol. 47, pp. 1853- 1860 ,(2014) , 10.1021/AR500073A
Martial Piotto, Vladimir Saudek, Vladimir Sklenář, Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. Journal of Biomolecular NMR. ,vol. 2, pp. 661- 665 ,(1992) , 10.1007/BF02192855
Hyun-Jin Kang, Samantha Kendrick, Sidney M. Hecht, Laurence H. Hurley, The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules. Journal of the American Chemical Society. ,vol. 136, pp. 4172- 4185 ,(2014) , 10.1021/JA4109352
Hideyuki Kanehara, Masatsugu Mizuguchi, Kunihiko Tajima, Kenji Kanaori, Keisuke Makino, Spectroscopic evidence for the formation of four-stranded solution structure of oligodeoxycytidine phosphorothioate. Biochemistry. ,vol. 36, pp. 1790- 1797 ,(1997) , 10.1021/BI961528C
Anh Tuân Phan, Maurice Guéron, Jean-Louis Leroy, The solution structure and internal motions of a fragment of the cytidine-rich strand of the human telomere Journal of Molecular Biology. ,vol. 299, pp. 123- 144 ,(2000) , 10.1006/JMBI.2000.3613
Jungkweon Choi, Tetsuro Majima, Conformational changes of non-B DNA. Chemical Society Reviews. ,vol. 40, pp. 5893- 5909 ,(2011) , 10.1039/C1CS15153C