Combination preparation comprising angiotensin-ii-receptor blocker and hmg-coa reductase inhibitor

作者: Sung Soo Jun , Ja Seong Koo , Jae Woon Son , Sung Wuk Kim , Young Gwan Jo

DOI:

关键词: Active ingredientHMG-CoA reductaseCombination therapyAngiotensin receptorBiochemistryNon-competitive inhibitionPharmacologyReductaseChemistry

摘要: Disclosed herein is a combination therapy and preparation of an angiotensin-II-receptor blocker HMG-CoA reductase inhibitor characterized in that the absorbed substantially later than inhibitor. As are released at different times, present prevents competitive inhibition between two drugs side effects, as well simultaneously provides synergistic effects for each active ingredient convenience taking drugs.

参考文章(5)
Sung Soo Jun, Ja Seong Koo, Jae Woon Son, Sung Wuk Kim, Young Gwan Jo, Controlled release complex composition comprising angiotensin-II-receptor blockers and HMG-CoA reductase inhibitors ,(2007)
David John Carini, John Jonas Vytautas Duncia, Angiotensin II receptor blocking imidazoles ,(1987)
Niall M. M. Fanning, Paul Stark, John G. Devane, Multiparticulate modified release composition ,(1999)
Hiroshi Tomiyama, Akira Tomiyama, Keiichiro Hayashi, Hidetoshi Miyamoto, Seiichiro Mochizuki, Drug for treating or preventing duplication of hypertension with serum hyperuricemia and/or hypercholesterolemia ,(2004)