作者: Evelyn Minis , Antonio Fernandes Moron , Alan Hatanaka , Stephanno GP Sarmento , Marcelo Santucci
关键词: Obstetrics 、 Gestation 、 Vaginal microbiome 、 Short cervix 、 Black women 、 Medicine 、 Transvaginal ultrasound 、 Cervical length 、 Pregnancy 、 Medical history
摘要: Objectives Short cervical length is a predictor of preterm birth. We evaluated if there were racial differences in variables associated with pregnant Brazilian women. Methods Cervical was determined by vaginal ultrasound 414 women at 21 weeks gestation. All seen the same clinic and analyzed investigators. Women found to have short cervix (≤25 mm) received progesterone throughout Composition microbiome analysis V1-V3 region gene coding for bacterial 16S ribosomal RNA. Demographic, clinical outcome chart review. Subjects 53.4% White, 37.2% mixed race 9.4% Black. Results: Pregnancy, medical history education level similar all groups. Mean shorter Black (28.4 than White (32.4 or (32.8 (p≤0.016) as percentage (23.1, 12.2, 7.8% Black, respectively) (p≤0.026). increased maternal age (p=0.001) (p=0.045) but not There no dominance microbiota between Most delivered term. Conclusions conclude that Brazil independent age, pregnancy demographic composition microbiome.