Natural acquired humoral immunity against serotype-specific group B Streptococcus rectovaginal colonization acquisition in pregnant women
作者： G. Kwatra , P.V. Adrian , T. Shiri , E.J. Buchmann , C.L. Cutland
DOI: 10.1016/J.CMI.2015.01.030
关键词: Colonization 、 Serotype 、 Humoral immunity 、 Group B 、 Microbiology 、 Pregnancy 、 Immunology 、 Biology 、 Antibody 、 Latex fixation test 、 Streptococcus
摘要: Group B Streptococcus (GBS) rectovaginal colonization in pregnant women is associated with invasive GBS disease newborns, preterm delivery and stillbirths. We studied the association of serotype-specific capsular polysaccharide (CPS) antibody on new acquisition clearance from 20 weeks until 37 to 40 weeks' gestation. Serum CPS IgG concentration was measured by multiplex enzyme-linked immunosorbent assay opsonophagocytic activity (OPA) titres. Rectovaginal swabs were evaluated for colonization, using standard culture methods serotyping latex agglutination, at five six weekly intervals. Higher serotype III lower risk during pregnancy (p 0.009). Furthermore, OPA titres Ia higher who remained free throughout study compared those acquired homotypic <0.001 both serotypes). values ≥1μg/mL V ≥3μg/mL serotypes significantly protection against serotype. A vaccine that induces sufficient women, including high titres, could protect latter half pregnancy.
clinicalmicrobiologyandinfection.com
core.ac.uk
warwick.ac.uk
sci-hub.se 参考文章(35)
Carol J. Baker, Bette J. Webb, Dennis L. Kasper, Martha D. Yow, Craig W. Beachler, The natural history of group B streptococcal colonization in the pregnant woman and her offspring American Journal of Obstetrics and Gynecology. ,vol. 137, pp. 39- 42 ,(1980) , 10.1016/0002-9378(80)90383-X
B F Anthony, N F Concepcion, C A Wass, D C Heiner, Immunoglobulin G and M composition of naturally occurring antibody to type III group B streptococci. Infection and Immunity. ,vol. 46, pp. 98- 104 ,(1984) , 10.1128/IAI.46.1.98-104.1984
C. Poyart, A. Tazi, H. Reglier-Poupet, A. Billoet, N. Tavares, J. Raymond, P. Trieu-Cuot, Multiplex PCR Assay for Rapid and Accurate Capsular Typing of Group B Streptococci Journal of Clinical Microbiology. ,vol. 45, pp. 1985- 1988 ,(2007) , 10.1128/JCM.00159-07
Sonela A. Schlottmann, Neil Jain, Narendra Chirmule, Mark T. Esser, A novel chemistry for conjugating pneumococcal polysaccharides to Luminex microspheres. Journal of Immunological Methods. ,vol. 309, pp. 75- 85 ,(2006) , 10.1016/J.JIM.2005.11.019
Kousaku Matsubara, Kazuaki Katayama, Kunizo Baba, Hiroyuki Nigami, Hidekazu Harigaya, Masako Sugiyama, Seroepidemiologic Studies of Serotype VIII Group B Streptococcus in Japan The Journal of Infectious Diseases. ,vol. 186, pp. 855- 858 ,(2002) , 10.1086/342411
Morven S. Edwards, Bernard Gonik, Preventing the Broad Spectrum of Perinatal Morbidity and Mortality Through Group B Streptococcal Vaccination Vaccine. ,vol. 31, ,(2013) , 10.1016/J.VACCINE.2012.11.046
Jean R. Goodman, Richard L. Berg, Robert K. Gribble, Paul R. Meier, Susan C. Fee, Paul D. Mitchell, Longitudinal study of group B streptococcus carriage in pregnancy. Infectious Diseases in Obstetrics & Gynecology. ,vol. 5, pp. 237- 243 ,(1997) , 10.1002/(SICI)1098-0997(1997)5:3<237::AID-IDOG9>3.0.CO;2-1
Paul T Heath, Robert G Feldman, Vaccination against Group B streptococcus Expert Review of Vaccines. ,vol. 4, pp. 207- 218 ,(2005) , 10.1586/14760584.4.2.207
S. M. Hansen, N. Uldbjerg, M. Kilian, U. B. S. Sorensen, Dynamics of Streptococcus agalactiae Colonization in Women during and after Pregnancy and in Their Infants Journal of Clinical Microbiology. ,vol. 42, pp. 83- 89 ,(2004) , 10.1128/JCM.42.1.83-89.2004
Stephanie J Schrag, Group B streptococcal vaccine for resource-poor countries. The Lancet. ,vol. 378, pp. 11- 12 ,(2011) , 10.1016/S0140-6736(10)61932-0