A molecular and bioinformatic study on the ochratoxin A (OTA)-producing Aspergillus affinis (section Circumdati )
作者： Domenico Davolos , Biancamaria Pietrangeli
DOI: 10.1007/S12550-014-0195-1
关键词: Polyketide synthase 、 Biology 、 Aspergillus species 、 Biosynthesis 、 Phylogenetic tree 、 Aspergillus 、 Botany 、 Gene 、 Ochratoxin A
摘要: Aspergillus affinis (section Circumdati) is a novel ochratoxin A (OTA)-producing species found in submerged riparian decomposing leaves. However, very little known about its role on the breakdown of plant debris and ability to degrade carbohydrate polymers. Moreover, OTA biosynthetic pathway has not yet been explored. In present paper, we investigated gene encoding extracellular alpha-amylase (amyAa) A. within evolution lineages relation possible use this enzyme starch processing. The amyAa, despite being related branches sections Terrei Flavi, formed distinct phylogenetic branch, which may be outstanding importance from biotechnological point view. identified polyketide synthase (pks) putatively required for first step biosynthesis affinis. This otapks was examined limited number orthologous genes available Circumdati Nigri. Our study highlights as target treatment ochratoxigenic more comprehensive evolutionary basis.
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