Role of Exercise Training in the Prevention and Treatment of Insulin Resistance and Non-Insulin-Dependent Diabetes Mellitus
作者： John L. Ivy
DOI: 10.2165/00007256-199724050-00004
关键词: Physical exercise 、 Diabetes mellitus 、 Pancreatic hormone 、 Insulin resistance 、 Carbohydrate metabolism 、 Impaired glucose tolerance 、 Glucose tolerance test 、 Insulin 、 Endocrinology 、 Internal medicine 、 Medicine
摘要: Recent epidemiological studies indicate that individuals who maintain a physically active lifestyle are much less likely to develop impaired glucose tolerance and non-insulin-dependent diabetes mellitus (NIDDM). Moreover, it was found the protective effect of physical activity strongest for at highest risk developing NIDDM. Reducing insulin resistance NIDDM by regularly performed exercise is also supported several aging studies. It has been older vigorously train on regular basis exhibit greater lower response challenge than sedentary similar age weight.
springer.com
sci-hub.se 参考文章(123)
Marco Crettaz, Marc Prentki, Daniel Zaninetti, Bernard Jeanrenaud, Insulin resistance in soleus muscle from obese Zucker rats. Involvement of several defective sites Biochemical Journal. ,vol. 186, pp. 525- 534 ,(1980) , 10.1042/BJ1860525
M. A. Rogers, D. S. King, J. M. Hagberg, A. A. Ehsani, J. O. Holloszy, Effect of 10 days of physical inactivity on glucose tolerance in master athletes Journal of Applied Physiology. ,vol. 68, pp. 1833- 1837 ,(1990) , 10.1152/JAPPL.1990.68.5.1833
S. Lund, H. Vestergaard, P. H. Andersen, O. Schmitz, L. B. Gotzsche, O. Pedersen, GLUT-4 content in plasma membrane of muscle from patients with non-insulin-dependent diabetes mellitus. American Journal of Physiology-endocrinology and Metabolism. ,vol. 265, ,(1993) , 10.1152/AJPENDO.1993.265.6.E889
K. J. Mikines, E. A. Richter, F. Dela, H. Galbo, Seven days of bed rest decrease insulin action on glucose uptake in leg and whole body Journal of Applied Physiology. ,vol. 70, pp. 1245- 1254 ,(1991) , 10.1152/JAPPL.1991.70.3.1245
P Björntorp, M Krotkiewski, Muscle tissue in obesity with different distribution of adipose tissue. Effects of physical training International Journal of Obesity. ,vol. 10, pp. 331- 341 ,(1986)
John O. Holloszy, H.T. Narahara, Studies of tissue permeability. X. Changes in permeability to 3-methylglucose associated with contraction of isolated frog muscle. Journal of Biological Chemistry. ,vol. 240, pp. 3493- 3500 ,(1965) , 10.1016/S0021-9258(18)97170-X
G. L. Dohm, M. K. Sinha, J. F. Caro, Insulin receptor binding and protein kinase activity in muscles of trained rats American Journal of Physiology-endocrinology and Metabolism. ,vol. 252, ,(1987) , 10.1152/AJPENDO.1987.252.2.E170
Tetsuro Kono, Frances W. Barham, The relationship between the insulin-binding capacity of fat cells and the cellular response to insulin. Studies with intact and trypsin-treated fat cells. Journal of Biological Chemistry. ,vol. 246, pp. 6210- 6216 ,(1971) , 10.1016/S0021-9258(18)61777-6
J R Williamson, E T Browning, R Scholz, Control Mechanisms of Gluconeogenesis and Ketogenesis I. EFFECTS OF OLEATE ON GLUCONEOGENESIS IN PERFUSED RAT LIVER Journal of Biological Chemistry. ,vol. 244, pp. 4607- 4616 ,(1969) , 10.1016/S0021-9258(18)93668-9
M F Hirshman, L J Goodyear, L J Wardzala, E D Horton, E S Horton, Identification of an intracellular pool of glucose transporters from basal and insulin-stimulated rat skeletal muscle Journal of Biological Chemistry. ,vol. 265, pp. 987- 991 ,(1990) , 10.1016/S0021-9258(19)40147-6