Nano-Interstice Driven Powerless Blood Plasma Extraction in a Membrane Filter Integrated Microfluidic Device
作者： Jaehoon Kim , Junghyo Yoon , Jae-Yeong Byun , Hyunho Kim , Sewoon Han
DOI: 10.3390/S21041366
关键词: Extraction (chemistry) 、 Membrane 、 Blood plasma 、 Plasma 、 Microfluidics 、 Materials science 、 Biomedical engineering 、 Leakage (electronics) 、 Nano- 、 Whole blood
摘要: Blood plasma is a source of biomarkers in blood and simple, fast, easy extraction method highly required for point-of-care testing (POCT) applications. This paper proposes membrane filter integrated microfluidic device to extract from whole blood, without any external instrumentation. A commercially available was with newly designed dual-cover avoid leakage the extracted remaining cells. Nano-interstices installed on both sides channels actively draw membrane. The developed successfully supplied 20 μL high yield (~45%) 16 min.
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