Analgesic medication use and risk of epithelial ovarian cancer in African American women

摘要: Existing literature examining analgesic medication use and epithelial ovarian cancer (EOC) risk has been inconsistent, with the majority of studies reporting an inverse association. Race-specific effects this relationship have not adequately addressed. Utilising data from largest population-based case–control study EOC in African Americans, American Cancer Epidemiology Study, between (aspirin, non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen) was estimated by multivariate logistic regression. The association frequency, duration, indication on also assessed. Aspirin use, overall, associated a 44% lower (OR=0.56; 95% CI=0.35–0.92) 26% observed for NSAID (OR=0.74; CI=0.52–1.05). strongest women taking aspirin to prevent cardiovascular disease NSAIDs arthritis. Significantly decreased risks were low-dose daily <5 years, occasional duration ⩾5 years. No acetaminophen use. Collectively, these findings support previous evidence that any is inversely risk.