Relation of vitamin A and carotenoid status to growth failure and mortality among Ugandan infants with human immunodeficiency virus.

摘要: Although growth failure is common during pediatric infection with human immunodeficiency virus (HIV) and associated increased mortality, the relation of specific nutrition factors mortality has not been well characterized. A longitudinal study was conducted 194 HIV-infected infants in Kampala, Uganda. Plasma vitamin A, carotenoids (α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein/zeaxanthin), E were measured at age 14 wk, weight height followed up to 12 mo. Vitamin low plasma carotenoid concentrations predictive decreased velocity. Between ages wk mo, 32% died. Underweight, stunting, risk death univariate analyses. death. In a final multivariate model adjusting for weight-for-age, β-carotene significantly (odds ratio: 3.16, 95% confidence interval: 1.38 7.21, P < 0.006). These data suggest that are HIV among