Progress in prokaryotic transcriptomics
作者： Melanie J Filiatrault
DOI: 10.1016/J.MIB.2011.07.023
关键词: RNA 、 Transcriptome 、 Bioinformatics 、 Computational biology 、 Gene expression 、 Biology 、 Ribosomal RNA 、 Regulation of gene expression 、 MOLECULAR BIOLOGY METHODS 、 Prokaryotic cells
摘要: Genome-wide expression studies transformed the field of transcriptomics and made it feasible to study global gene in extraordinary detail. These new methods have revealed an enhanced view transcriptional landscape yielded many biological insights. It is increasingly clear that prokaryotic transcriptome much more complex than once thought. Recent advances microbial analyses are highlighted this review. Areas progress include development optimized techniques minimize abundance ribosomal RNAs RNA samples as well novel create libraries. Advances such these led a emphasis areas metatranscriptomics single cell studies.
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