Biologic Preparation of Diseased Root Surfaces

摘要: Untreated periodontally-involved teeth contain cementum-bound endotoxin, that may prevent periodontal new attachment during healing after pocket therapy. The purpose of this study was to restore biocompatibiltty diseased root surfaces by a non-invasive treatment. human removed for severe chronic disease were split buccolingually, the level connective tissue scribed on roots, specimens cleaned plaque and visible calculus, autoclaved. Cementum removal not attempted. One member each pair treated with phosphate-buffered saline as control. Sodium desoxycholate (2%), Cohn plasma fraction IV1 (5%), or deoxycholate followed applied one minute. Roots incubated in suspension gingival fibroblasts 48 hours, then rinsed, fixed, stained. Counts made number attached cells at 40 × magnification using an ocular grid. There significant increase (p < 0.01) combination treatment over con...