Analysis of the role of PCNA-DNA contacts during clamp loading.

作者: Randall McNally , Gregory D Bowman , Eric R Goedken , Mike O'Donnell , John Kuriyan

DOI: 10.1186/1472-6807-10-3

关键词: ReplisomeProcessivitydnaNDNA clampBiophysicsDNA polymerase deltaBiologyProliferating cell nuclear antigenDNA polymeraseBiochemistryDNA replication

摘要: Sliding clamps, such as Proliferating Cell Nuclear Antigen (PCNA) in eukaryotes, are ring-shaped protein complexes that encircle DNA and enable highly processive DNA replication …

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