Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2018

摘要: Several studies published over the last two decades have provided a good body of evidences supporting central role chronic low-grade inflammation as major factor driving many metabolic complications commonly found in highly prevalent diseases such obesity, insulin resistance, and cancer. It was well established these studies, for example, that activation canonical inflammatory pathways is one factors promoting impairment signaling seen obesity type 2 diabetes, being responsible reduced glucose uptake exacerbated lipolysis this condition. Such important has motivated several aiming at understanding mechanisms underlying its development searching efficient therapeutic strategies to minimize consequences. In present special issue, we gathered original review articles addressing potential nutritional, pharmacological, behavioral could be used counteract process associated with variety including periodontal disease, myocardial infarction, pneumonia, among others. very interesting study, E. G. Novoselova et al. experimentally tested individually or combination inhibitors NFkB pathway naturally occurring antioxidants anti-inflammatory agents vivo bringing new information about their efficacy. same direction, M. S. Elburki appropriateness using novel chemically modified curcumin, matrix metalloproteinase inhibitor no antibiotic properties, molecule treatment disease promising results towards attenuation alveolar bone loss.