Diagnosis and Management of the Metabolic Syndrome An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement: Executive Summary

摘要: This Executive Summary is a synopsis of the full scientific statement from American Heart Association (AHA) and National Heart, Lung, Blood Institute (NHLBI), which intended to provide up date guidance for professionals on diagnosis management metabolic syndrome in adults. The has received increased attention past few years. It consists multiple, interrelated risk factors origin that appear directly promote development atherosclerotic cardiovascular disease (ASCVD). constellation strongly associated with type 2 diabetes mellitus or this condition. The consist atherogenic dyslipidemia (elevated triglycerides apolipoprotein B, small LDL particles, low HDL cholesterol [HDL-C] concentrations), elevated blood pressure, plasma glucose, prothrombotic state, proinflammatory state. At present, it not clear whether single cause, appears can be precipitated by multiple underlying factors. most important these are abdominal obesity insulin resistance. Other conditions include physical inactivity, aging, hormonal imbalance, genetic ethnic predisposition. Prospective population studies show confers an &2-fold increase relative ASCVD events, individuals without established mellitus, &5-fold developing as compared people syndrome. finding implies imparts relatively high long-term both diabetes. In absence diabetes, absolute short-term (10-year) major coronary heart (CHD) events necessarily high. Framingham Study data, 10-year CHD depends other addition components contained scoring …