作者: Lili Fan , Donald R. Owen
DOI:
关键词: Fibroblast 、 Cell turnover 、 Micelle 、 Aqueous solution 、 Extracellular 、 Matrix (biology) 、 Chromatography 、 Materials science 、 Biochemistry
摘要: Oligomeric acylated biosurfactants (“OABs”) having low critical micelle concentrations of from about 1.0 ppm to 200 ppm, preferably less than 50 in an aqueous solution Minimal Essential Media that can lower the surface tension MEM environment dynes/cm 2 and have ability increase metabolic soluble proteins and/or synthesis extracellular skin matrix rates cell turnover while at same time exhibiting comparatively toxicity—preferably, LD greater 37 year-old female fibroblast cells. Another aspect present invention is directed use OABs formulations are topically-applied, by which meant formulation placed direct contact with skin, hair nails as well mucosa eyes, ears, nose, mouth, anus vagina.